The outbreak of the Ebola virus disease in 2014 and COVID-19 pandemic in 2020 reinforced the urgency for ECOWAS member states to strengthen their pharmaceutical industry, improve the business environment to boost local production of essential medicines as well as reduce its dependency on global value-chains for medical supplies and build resilience in the sector. The Project of Development of the Pharmaceutical Industry (DPI) Industry is a regional undertaking conceived to support ECOWAS pharmaceutical institutions, including the Medicines Regulatory Authorities (MRAs), quality control laboratories, and regional pharmaceutical training institutions. This project is supported by the African Development Bank and aim to strengthen the pharmaceutical sector to boost local production of safe, quality, and affordable medicines and vaccines in the ECOWAS region to meet the healthcare services and needs of the population.